Ibrance vs Calquence
Side-by-side drug price comparison from Medicare Part D data
Verdict
Calquence costs 7% less per claim than Ibrance ($10105.00 vs $10816.00). Ibrance has a generic alternative available. Total Medicare spending: Ibrance at $4.5B vs Calquence at $2.9B.
| Metric | Ibrance | Calquence |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $10,816 | $10,105* |
| Total Medicare Spending Total Medicare Part D spending on this drug | $4.5B | $2.9B |
| Total Claims | 418,000 | 286,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | -5.6%* | 34.2% |
| Generic Available | Yes | Yes |
| Condition | Cancer | Cancer |
| Total Beneficiaries | 36,000 | 28,000 |
Calquence costs 7% less per claim than Ibrance ($10105.00 vs $10816.00). Ibrance has a generic alternative available. Total Medicare spending: Ibrance at $4.5B vs Calquence at $2.9B.
Explore More
The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both Ibrance and Calquence. What follows is the interpretation — which specific axes carry the most weight for Ibrance versus Calquence, and which differences are large enough to influence a real decision.
For households or analysts using this comparison as a decision input, the right framing is usually not "which is better" in aggregate but "which is better for the specific decision in front of you." CMS Medicare Part D Drug Spending data captures the raw data; the framing depends on whether the question is investment, residency, planning, or research.
Source: CMS Medicare Part D Spending, 2026.