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DrugPrice

Drug Pricing Transparency · Updated Apr 2026

Why Does This Drug
Cost This Much?

Search 507 prescription drugs. See what Medicare pays per claim, track patent expirations, and find when generics launch.

Try: Ozempic, Eliquis, Humira, Keytruda

507
Drugs Tracked
$355.8B
Medicare Spending
231,460,840
Beneficiaries
95%
Have Generic

Medicare Negotiated Prices

View all 25 drugs

For the first time, Medicare can negotiate drug prices directly with manufacturers.25 drugs now have Maximum Fair Prices under the Inflation Reduction Act.

-79%
Januvia
$527.00
$113.00
-76%
Fiasp/NovoLog
$495.00
$119.00
-68%
Farxiga
$556.00
$178.00
-67%
Enbrel
$7,106.00
$2,355.00
-66%
Jardiance
$573.00
$197.00

Highest Medicare Spending

View all

Eliquis

Apixaban

Blood Clots

$16.6B Medicare spending
$510.00
per claim
Generic available
+14.2% YoY

Revlimid

Lenalidomide

Cancer

$7.8B Medicare spending
$12,786.00
per claim
Brand only
-3.4% YoY

Keytruda

Pembrolizumab

Cancer

$7.2B Medicare spending
$18,176.00
per claim
Brand only
+28.6% YoY

Humira

Adalimumab

Autoimmune Diseases

$6.5B Medicare spending
$3,414.00
per claim
Generic available
-22.1% YoY

Imbruvica

Ibrutinib

Cancer

$5.7B Medicare spending
$10,445.00
per claim
Generic available
-8.7% YoY

Stelara

Ustekinumab

Autoimmune Diseases

$5.6B Medicare spending
$7,763.00
per claim
Generic available
+6.3% YoY

Opdivo

Nivolumab

Cancer

$5.1B Medicare spending
$15,821.00
per claim
Generic available
+15.8% YoY

Xarelto

Rivaroxaban

Blood Clots

$5.0B Medicare spending
$321.00
per claim
Generic available
-1.2% YoY

Ozempic

Semaglutide

Diabetes

$5.0B Medicare spending
$685.00
per claim
Brand only
+72.5% YoY

Entresto

Sacubitril/Valsartan

Heart Failure

$4.8B Medicare spending
$379.00
per claim
Brand only
+18.3% YoY

Ibrance

Palbociclib

Cancer

$4.5B Medicare spending
$10,816.00
per claim
Generic available
-5.6% YoY

Dupixent

Dupilumab

Autoimmune Diseases

$4.4B Medicare spending
$2,819.00
per claim
Brand only
+35.2% YoY

Compare by Drug Class

View all classes

Statins (Cholesterol-Lowering)

From $16/claim to $757/claim · 8 drugs

Blood Pressure Medications (Antihypertensives)

From $6/claim to $144/claim · 7 drugs

Diabetes Medications

From $4/claim to $685/claim · 13 drugs

GLP-1 Receptor Agonists (Weight Loss & Diabetes)

From $149/claim to $867/claim · 7 drugs

Antidepressants (SSRIs, SNRIs & Newer Agents)

From $4/claim to $1839/claim · 7 drugs

Blood Thinners (Anticoagulants)

From $8/claim to $510/claim · 7 drugs

Browse by Condition

Cancer

81 drugs · $92.5B total spending

Diabetes

41 drugs · $40.0B total spending

Autoimmune Diseases

23 drugs · $39.7B total spending

Blood Clots

11 drugs · $24.5B total spending

HIV

18 drugs · $16.7B total spending

Multiple Sclerosis

18 drugs · $15.1B total spending

Asthma/COPD

18 drugs · $14.5B total spending

Mental Health

20 drugs · $10.6B total spending

Eye Diseases

17 drugs · $9.4B total spending

High Cholesterol

19 drugs · $7.5B total spending

Pulmonary Hypertension

9 drugs · $6.0B total spending

Blood Disorders

8 drugs · $6.0B total spending

Generic Watch

Drugs losing patent protection soon — track when cheaper generics launch

Biosimilar Tracker

30+ biosimilars for Humira, Stelara, Enbrel — with discount comparisons

Biggest Price Increases

Drugs with the steepest year-over-year cost increases in Medicare

Compare Drugs

Side-by-side cost comparison for drugs that treat the same condition

Learn About Drug Pricing

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Guide

How Drug Pricing Works

The complete guide to WAC, PBMs, and why drugs cost what they do

Guide

GLP-1 Pricing Guide

Ozempic vs Wegovy vs Mounjaro — costs, savings, and Medicare prices

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TrumpRx vs GoodRx vs Cost Plus

Which drug discount program saves you the most?

Guide

Cheapest Drugs by Class

Find the lowest-cost option for every major drug category

Frequently Asked Questions

Where does this pricing data come from?

All spending data comes from the CMS Medicare Part D Drug Spending Dashboard, which is public data published by the Centers for Medicare & Medicaid Services. Patent and generic information comes from the FDA Orange Book.

What does "average cost per claim" mean?

This is the average amount Medicare pays per 30-day supply claim for a drug. It includes both the plan's payment and the beneficiary's out-of-pocket cost. Your actual cost depends on your specific plan and coverage tier.

What is the Generic Watch?

The Generic Watch tracks drugs whose patents are expiring soon. When a patent expires, generic manufacturers can produce lower-cost versions, often reducing prices by 80-95%. This is especially important for high-cost drugs like GLP-1 agonists.