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DrugPrice

Repatha

Evolocumab

$757.00
avg cost per claim
+24.6% year-over-year
$2.6B
Medicare Spending
3,420,000
Total Claims
398,000
Beneficiaries
$6,505.00
Annual Cost/Patient

Why Repatha Costs $757.00 Per Claim

Repatha (Evolocumab) is used to treat high cholesterol. According to CMS Medicare Part D spending data, the program spent $2.6B on this drug, covering 398,000 beneficiaries across 3,420,000 claims.

This drug is currently protected by patents expiring Aug 27, 2029. Until patent protection ends, no generic version can enter the market, which limits price competition. Once generics become available, the price typically drops 80-95%.

Spending on Repatha increased by +24.6% year-over-year, driven by increased utilization among Medicare beneficiaries.

Price Breakdown

Avg cost per claim (30-day)$757.00
Avg annual cost per patient$6,505.00
Total Medicare spending$2.6B
Total claims3,420,000
Beneficiaries398,000

Drug Details

Brand Name
Repatha
Generic Name
Evolocumab
Active Ingredient
EVOLOCUMAB
Manufacturer
Amgen
Dosage Form
INJECTABLE
Route
INJECTION
Condition
High Cholesterol
FDA Application
BLA125522

Frequently Asked Questions

Repatha (Evolocumab) costs an average of $757.00 per claim based on Medicare Part D data. The estimated annual cost per patient is $6,505.00. Actual out-of-pocket costs depend on your insurance plan and pharmacy.

Repatha averages $757.00 per Medicare Part D claim — roughly equivalent to a 30-day supply for most patients on standard dosing. Without insurance, expect higher cash-pay prices unless you use a discount program (GoodRx, SingleCare, manufacturer copay assistance). With Medicare or commercial insurance, your out-of-pocket cost depends on your plan's formulary tier and deductible status.

A typical 30-day supply of Repatha reflects in our Medicare Part D average of $757.00 per claim. No generic is available yet, so cost remains at brand-name pricing. Cash-pay prices vary by pharmacy — comparison shopping (or using GoodRx coupons) often saves 20-50% off the listed price.

Most commercial insurance plans and Medicare Part D plans cover Repatha, but coverage varies by formulary tier. Repatha is often Tier 2 or Tier 3 on most formularies, meaning a higher copay than generic alternatives. Some plans require prior authorization or step therapy. Check your plan's formulary or call the number on your insurance card to confirm.

Several options for cash-pay patients: (1) Manufacturer patient assistance programs — the manufacturer may offer copay cards or free-drug programs for income-qualified patients; (2) Discount programs like GoodRx, SingleCare, or RxSaver typically save 20-80% off the cash price; (3) Mark Cuban's Cost Plus Drugs offers transparent generic pricing if a generic is available; (4) 340B-eligible community health centers offer drugs at federally negotiated discounts. Patient assistance programs are the primary affordability path while no generic is available.

Repatha is still under patent protection until Aug 27, 2029, giving the manufacturer market exclusivity. Once the patent expires, generics enter the market and prices typically fall 80-95% within 1-2 years.

No, Repatha is currently brand-only. Patent protection expires Aug 27, 2029, after which generic versions may enter the market.

Medicare Part D spent $2.6B on Repatha, covering 398,000 beneficiaries across 3,420,000 claims. This makes it one of the tracked drugs in the Medicare spending dashboard.

Check manufacturer patient assistance programs for potential savings. You can also compare prices at different pharmacies, use prescription discount programs (GoodRx, SingleCare, Cost Plus Drugs), or ask your doctor about therapeutic alternatives in the same drug class.

this entity is one of the data points covered by this site’s U.S. Medicare prescription-drug pricing dataset. The detail above comes directly from CMS Medicare Part D Drug Spending data; the context that follows situates the headline numbers against the broader distribution across U.S. prescription drugs.

The methodology behind every numeric value on this page is publicly documented on the CMS Medicare Part D Drug Spending data portal and described in detail on this site’s methodology page. Refresh cadence varies by underlying series; the page surfaces the as-of date for each number so readers can trace any figure back to the source release.

Practical use of this page is in combination with the comparison and ranking pages elsewhere on the site, which surface the same data for this entity’s peers within U.S. prescription drugs. A single-entity reading without peer context can be misleading when an entity is an outlier on one axis but typical on another.

Cost data reflects Medicare Part D spending and may not represent retail pharmacy prices. Average cost per claim represents the total drug cost (not patient out-of-pocket) divided by total claims.