Imbruvica vs Trulicity
Side-by-side drug price comparison from Medicare Part D data
Verdict
Trulicity costs 95% less per claim than Imbruvica ($473.00 vs $10445.00). Imbruvica has a generic alternative available. Total Medicare spending: Imbruvica at $5.7B vs Trulicity at $4.2B.
| Metric | Imbruvica | Trulicity |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $10,445 | $473* |
| Total Medicare Spending Total Medicare Part D spending on this drug | $5.7B | $4.2B |
| Total Claims | 548,000 | 8,920,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | -8.7%* | -4.8% |
| Generic Available | Yes | No |
| Condition | Cancer | Diabetes |
| Total Beneficiaries | 48,000 | 985,000 |
Trulicity costs 95% less per claim than Imbruvica ($473.00 vs $10445.00). Imbruvica has a generic alternative available. Total Medicare spending: Imbruvica at $5.7B vs Trulicity at $4.2B.
Explore More
Comparing Imbruvica and Trulicity on U.S. Medicare prescription-drug pricing requires lining up the underlying CMS Medicare Part D Drug Spending data data side by side. The table above runs the comparison on the canonical fields; the narrative below identifies the factor or factors that drive the most meaningful difference between the two.
Practical use of the comparison: read the data above, then drill into the individual Imbruvica and Trulicity detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.