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Januvia vs Mounjaro

Side-by-side drug price comparison from Medicare Part D data

Reviewed by DrugPrice Editorial Team · Updated

Verdict

Januvia costs 67% less per claim than Mounjaro ($219.00 vs $673.00). Neither drug has a generic alternative available. Total Medicare spending: Januvia at $2.7B vs Mounjaro at $2.5B.

MetricJanuviaMounjaro
Avg Cost per Claim
Average cost Medicare pays per prescription claim
$219*$673
Total Medicare Spending
Total Medicare Part D spending on this drug
$2.7B$2.5B
Total Claims12,480,0003,680,000
Year-over-Year Change
Price change from prior year (lower is better for patients)
-12.3%*312.4%
Generic AvailableNoNo
ConditionDiabetesDiabetes
Total Beneficiaries1,560,000524,000

Januvia costs 67% less per claim than Mounjaro ($219.00 vs $673.00). Neither drug has a generic alternative available. Total Medicare spending: Januvia at $2.7B vs Mounjaro at $2.5B.

Explore More

The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both Januvia and Mounjaro. What follows is the interpretation — which specific axes carry the most weight for Januvia versus Mounjaro, and which differences are large enough to influence a real decision.

For households or analysts using this comparison as a decision input, the right framing is usually not "which is better" in aggregate but "which is better for the specific decision in front of you." CMS Medicare Part D Drug Spending data captures the raw data; the framing depends on whether the question is investment, residency, planning, or research.

Source: CMS Medicare Part D Spending, 2026.