Jardiance vs Skyrizi
Side-by-side drug price comparison from Medicare Part D data
Verdict
Jardiance costs 95% less per claim than Skyrizi ($210.00 vs $4475.00). Jardiance has a generic alternative available. Total Medicare spending: Jardiance at $3.9B vs Skyrizi at $2.3B.
| Metric | Jardiance | Skyrizi |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $210* | $4,475 |
| Total Medicare Spending Total Medicare Part D spending on this drug | $3.9B | $2.3B |
| Total Claims | 18,760,000 | 524,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | 22.7%* | 42.8% |
| Generic Available | Yes | No |
| Condition | Diabetes | Autoimmune Diseases |
| Total Beneficiaries | 2,150,000 | 78,000 |
Jardiance costs 95% less per claim than Skyrizi ($210.00 vs $4475.00). Jardiance has a generic alternative available. Total Medicare spending: Jardiance at $3.9B vs Skyrizi at $2.3B.
Explore More
Comparing Jardiance and Skyrizi on U.S. Medicare prescription-drug pricing requires lining up the underlying CMS Medicare Part D Drug Spending data data side by side. The table above runs the comparison on the canonical fields; the narrative below identifies the factor or factors that drive the most meaningful difference between the two.
Practical use of the comparison: read the data above, then drill into the individual Jardiance and Skyrizi detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.