Ozempic vs Ocrevus
Side-by-side drug price comparison from Medicare Part D data
Verdict
Ozempic costs 97% less per claim than Ocrevus ($685.00 vs $23635.00). Ocrevus has a generic alternative available. Total Medicare spending: Ozempic at $5.0B vs Ocrevus at $3.5B.
| Metric | Ozempic | Ocrevus |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $685* | $23,635 |
| Total Medicare Spending Total Medicare Part D spending on this drug | $5.0B | $3.5B |
| Total Claims | 7,240,000 | 148,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | 72.5% | 16.5%* |
| Generic Available | No | Yes |
| Condition | Diabetes | Multiple Sclerosis |
| Total Beneficiaries | 1,180,000 | 62,000 |
Ozempic costs 97% less per claim than Ocrevus ($685.00 vs $23635.00). Ocrevus has a generic alternative available. Total Medicare spending: Ozempic at $5.0B vs Ocrevus at $3.5B.
Explore More
Comparing Ozempic and Ocrevus on U.S. Medicare prescription-drug pricing requires lining up the underlying CMS Medicare Part D Drug Spending data data side by side. The table above runs the comparison on the canonical fields; the narrative below identifies the factor or factors that drive the most meaningful difference between the two.
Practical use of the comparison: read the data above, then drill into the individual Ozempic and Ocrevus detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.