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Revlimid vs Calquence

Side-by-side drug price comparison from Medicare Part D data

Reviewed by DrugPrice Editorial Team · Updated

Verdict

Calquence costs 21% less per claim than Revlimid ($10105.00 vs $12786.00). Calquence has a generic alternative available. Total Medicare spending: Revlimid at $7.8B vs Calquence at $2.9B.

MetricRevlimidCalquence
Avg Cost per Claim
Average cost Medicare pays per prescription claim
$12,786$10,105*
Total Medicare Spending
Total Medicare Part D spending on this drug
$7.8B$2.9B
Total Claims612,000286,000
Year-over-Year Change
Price change from prior year (lower is better for patients)
-3.4%*34.2%
Generic AvailableNoYes
ConditionCancerCancer
Total Beneficiaries58,00028,000

Calquence costs 21% less per claim than Revlimid ($10105.00 vs $12786.00). Calquence has a generic alternative available. Total Medicare spending: Revlimid at $7.8B vs Calquence at $2.9B.

Explore More

The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both Revlimid and Calquence. What follows is the interpretation — which specific axes carry the most weight for Revlimid versus Calquence, and which differences are large enough to influence a real decision.

For households or analysts using this comparison as a decision input, the right framing is usually not "which is better" in aggregate but "which is better for the specific decision in front of you." CMS Medicare Part D Drug Spending data captures the raw data; the framing depends on whether the question is investment, residency, planning, or research.

Source: CMS Medicare Part D Spending, 2026.