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Revlimid vs Keytruda

Side-by-side drug price comparison from Medicare Part D data

Reviewed by DrugPrice Editorial Team · Updated

Verdict

Revlimid costs 30% less per claim than Keytruda ($12786.00 vs $18176.00). Neither drug has a generic alternative available. Total Medicare spending: Revlimid at $7.8B vs Keytruda at $7.2B.

MetricRevlimidKeytruda
Avg Cost per Claim
Average cost Medicare pays per prescription claim
$12,786*$18,176
Total Medicare Spending
Total Medicare Part D spending on this drug
$7.8B$7.2B
Total Claims612,000398,000
Year-over-Year Change
Price change from prior year (lower is better for patients)
-3.4%*28.6%
Generic AvailableNoNo
ConditionCancerCancer
Total Beneficiaries58,00082,000

Revlimid costs 30% less per claim than Keytruda ($12786.00 vs $18176.00). Neither drug has a generic alternative available. Total Medicare spending: Revlimid at $7.8B vs Keytruda at $7.2B.

Explore More

The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both Revlimid and Keytruda. What follows is the interpretation — which specific axes carry the most weight for Revlimid versus Keytruda, and which differences are large enough to influence a real decision.

For households or analysts using this comparison as a decision input, the right framing is usually not "which is better" in aggregate but "which is better for the specific decision in front of you." CMS Medicare Part D Drug Spending data captures the raw data; the framing depends on whether the question is investment, residency, planning, or research.

Source: CMS Medicare Part D Spending, 2026.