Stelara vs Eylea
Side-by-side drug price comparison from Medicare Part D data
Verdict
Eylea costs 90% less per claim than Stelara ($752.00 vs $7763.00). Stelara has a generic alternative available. Total Medicare spending: Stelara at $5.6B vs Eylea at $3.7B.
| Metric | Stelara | Eylea |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $7,763 | $752* |
| Total Medicare Spending Total Medicare Part D spending on this drug | $5.6B | $3.7B |
| Total Claims | 720,000 | 4,860,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | 6.3% | -8.3%* |
| Generic Available | Yes | Yes |
| Condition | Autoimmune Diseases | Eye Diseases |
| Total Beneficiaries | 114,000 | 685,000 |
Eylea costs 90% less per claim than Stelara ($752.00 vs $7763.00). Stelara has a generic alternative available. Total Medicare spending: Stelara at $5.6B vs Eylea at $3.7B.
Explore More
Comparing Stelara and Eylea on U.S. Medicare prescription-drug pricing requires lining up the underlying CMS Medicare Part D Drug Spending data data side by side. The table above runs the comparison on the canonical fields; the narrative below identifies the factor or factors that drive the most meaningful difference between the two.
Practical use of the comparison: read the data above, then drill into the individual Stelara and Eylea detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.