Stelara vs Opdivo
Side-by-side drug price comparison from Medicare Part D data
Verdict
Stelara costs 51% less per claim than Opdivo ($7763.00 vs $15821.00). Stelara has a generic alternative available. Total Medicare spending: Stelara at $5.6B vs Opdivo at $5.1B.
| Metric | Stelara | Opdivo |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $7,763* | $15,821 |
| Total Medicare Spending Total Medicare Part D spending on this drug | $5.6B | $5.1B |
| Total Claims | 720,000 | 324,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | 6.3%* | 15.8% |
| Generic Available | Yes | Yes |
| Condition | Autoimmune Diseases | Cancer |
| Total Beneficiaries | 114,000 | 66,000 |
Stelara costs 51% less per claim than Opdivo ($7763.00 vs $15821.00). Stelara has a generic alternative available. Total Medicare spending: Stelara at $5.6B vs Opdivo at $5.1B.
Explore More
The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both entity A and entity B. What follows is the interpretation — which specific axes carry the most weight for entity A versus entity B, and which differences are large enough to influence a real decision.
Practical use of the comparison: read the data above, then drill into the individual entity A and entity B detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.