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Xarelto vs Jardiance

Side-by-side drug price comparison from Medicare Part D data

Reviewed by DrugPrice Editorial Team · Updated

Verdict

Jardiance costs 35% less per claim than Xarelto ($210.00 vs $321.00). Xarelto has a generic alternative available. Total Medicare spending: Xarelto at $5.0B vs Jardiance at $3.9B.

MetricXareltoJardiance
Avg Cost per Claim
Average cost Medicare pays per prescription claim
$321$210*
Total Medicare Spending
Total Medicare Part D spending on this drug
$5.0B$3.9B
Total Claims15,680,00018,760,000
Year-over-Year Change
Price change from prior year (lower is better for patients)
-1.2%*22.7%
Generic AvailableYesYes
ConditionBlood ClotsDiabetes
Total Beneficiaries1,920,0002,150,000

Jardiance costs 35% less per claim than Xarelto ($210.00 vs $321.00). Xarelto has a generic alternative available. Total Medicare spending: Xarelto at $5.0B vs Jardiance at $3.9B.

Explore More

The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both Xarelto and Jardiance. What follows is the interpretation — which specific axes carry the most weight for Xarelto versus Jardiance, and which differences are large enough to influence a real decision.

For households or analysts using this comparison as a decision input, the right framing is usually not "which is better" in aggregate but "which is better for the specific decision in front of you." CMS Medicare Part D Drug Spending data captures the raw data; the framing depends on whether the question is investment, residency, planning, or research.

Source: CMS Medicare Part D Spending, 2026.