Xtandi vs Januvia
Side-by-side drug price comparison from Medicare Part D data
Verdict
Januvia costs 98% less per claim than Xtandi ($219.00 vs $9331.00). Xtandi has a generic alternative available. Total Medicare spending: Xtandi at $4.1B vs Januvia at $2.7B.
| Metric | Xtandi | Januvia |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $9,331 | $219* |
| Total Medicare Spending Total Medicare Part D spending on this drug | $4.1B | $2.7B |
| Total Claims | 438,000 | 12,480,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | 9.4% | -12.3%* |
| Generic Available | Yes | No |
| Condition | Cancer | Diabetes |
| Total Beneficiaries | 46,000 | 1,560,000 |
Januvia costs 98% less per claim than Xtandi ($219.00 vs $9331.00). Xtandi has a generic alternative available. Total Medicare spending: Xtandi at $4.1B vs Januvia at $2.7B.
Explore More
Comparing Xtandi and Januvia on U.S. Medicare prescription-drug pricing requires lining up the underlying CMS Medicare Part D Drug Spending data data side by side. The table above runs the comparison on the canonical fields; the narrative below identifies the factor or factors that drive the most meaningful difference between the two.
Practical use of the comparison: read the data above, then drill into the individual Xtandi and Januvia detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.