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Dermatology Drug Costs With Medicare

Compare 4 dermatology drug prices under Medicare Part D, averaging $417.00 per claim. Prices range from $285.00 (Eucrisa) to $718.00 (Adbry) per prescription. 4 of 4 drugs have FDA-approved generics that cost 30-80% less.

Key Facts: Dermatology Drug Costs

Cheapest drug
Eucrisa ($285.00)
Most expensive
Adbry ($718.00)
Medicare Part D avg
$417.00/claim
Generics available
4 of 4
Total Medicare spend
$713.0M/yr
Brand-only drugs
0

Source: CMS Medicare Part D Spending, latest reporting year. Costs reflect plan-paid amounts, not patient out-of-pocket.

Dermatology Drug Price Comparison

All 4 dermatology drugs tracked in Medicare Part D, sorted from cheapest to most expensive. Click any drug for Medicare coverage details, generic timelines, and savings options.

DrugGeneric NameMedicare Avg/ClaimGeneric Available?
EucrisaCrisaborole$285.00Yes
VtamaTapinarof$290.00Yes
OpzeluraRuxolitinib (topical)$375.00Yes
AdbryTralokinumab$718.00Yes

Medicare Part D Coverage for Dermatology Drugs

All 4 dermatology drugs in this comparison are dispensed under Medicare Part D. Total Medicare spending reached $713.0M in the latest reporting year, averaging $417.00 per prescription fill.

Your out-of-pocket cost depends on three factors: (1) your plan's formulary tier — generics typically land on Tier 1 ($0-$10 copay), preferred brands on Tier 2 ($30-$50), and specialty drugs on Tier 4-5 (often 25-33% coinsurance); (2) your deductible status — most plans require you to meet up to a $590 deductible before copays apply; (3) the coverage phase — initial coverage, coverage gap, or catastrophic. As of 2025, Medicare Part D caps total annual out-of-pocket at $2,000 under the Inflation Reduction Act.

The 4 drugs with generic availability are usually the most cost-effective starting point — ask your prescriber whether a generic substitution is clinically appropriate.

Drug costs vary dramatically within this category. Adbry (Tralokinumab) at $718.00 per claim is 3x more expensive than Eucrisa (Crisaborole) at $285.00 — yet both treat dermatology. Therapeutic substitution within the same drug class is often the single biggest savings lever, and it requires only a prescriber conversation, not a plan change.

Frequently Asked Questions

Medicare Part D pays an average of $417.00 per claim for dermatology medications across 4 tracked drugs. Patient out-of-pocket costs depend on your plan's formulary tier, deductible, and whether you've reached the catastrophic coverage phase. Most dermatology drugs fall on Tier 2 (preferred brand) or Tier 3 (non-preferred brand) of standard Medicare Part D formularies.

The least expensive dermatology medication is Eucrisa (Crisaborole) at $285.00 per Medicare Part D claim. A generic version is FDA-approved and available — ask your pharmacist about substitution to lower copays further.

Yes. All 4 dermatology drugs tracked here appear in Medicare Part D claims data, meaning they are dispensed under Part D plans. Coverage details — formulary tier, prior authorization requirements, step therapy — vary by plan. Check your plan's formulary or call 1-800-MEDICARE before filling.

Yes, 4 of 4 dermatology drugs have FDA-approved generic alternatives. Generics contain the same active ingredient and meet bioequivalence standards, but typically cost 30-80% less. On Medicare Part D, generics usually fall on Tier 1 with the lowest copay.

Three primary strategies: (1) Switch to a generic if available — Tier 1 generics typically cost under $10 per fill on Medicare Part D; (2) Use manufacturer copay assistance for brand-name drugs (commercial insurance only — Medicare beneficiaries can apply for patient assistance foundations like NeedyMeds or the PAN Foundation); (3) Compare cash prices using GoodRx, SingleCare, or Mark Cuban's Cost Plus Drugs — sometimes cash pay beats your Part D copay. Talk to your doctor about therapeutic alternatives in the same drug class.

Cost per claim is the average plan-paid amount per prescription fill under Medicare Part D. Patient out-of-pocket varies by formulary tier and deductible status. Generic availability is based on FDA Orange Book data.

Source: CMS Medicare Part D Spending, 2026.