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DrugPrice

Aranesp

Darbepoetin Alfa

Generic availableKidney Diseaseby Amgen
$457.00
avg cost per claim
-4.8% year-over-year
Reviewed by DrugPrice Editorial Team · Updated
$567.0M
Medicare Spending
1,240,000
Total Claims
86,000
Beneficiaries
$6,593.00
Annual Cost/Patient

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Why Aranesp Costs $457.00 Per Claim

Aranesp (Darbepoetin Alfa) is used to treat kidney disease. According to CMS Medicare Part D spending data, the program spent $567.0M on this drug, covering 86,000 beneficiaries across 1,240,000 claims.

A generic version of this drug is available, which means lower-cost alternatives exist. Patients should ask their pharmacist about generic Darbepoetin Alfa or talk to their doctor about therapeutic alternatives that may cost less.

Price Breakdown

Avg cost per claim (30-day)$457.00
Avg annual cost per patient$6,593.00
Total Medicare spending$567.0M
Total claims1,240,000
Beneficiaries86,000

Drug Details

Brand Name
Aranesp
Generic Name
Darbepoetin Alfa
Active Ingredient
Darbepoetin Alfa
Manufacturer
Amgen
Dosage Form
N/A
Route
N/A
Condition
Kidney Disease
FDA Application
BLA125057

Frequently Asked Questions

Aranesp (Darbepoetin Alfa) costs an average of $457.00 per claim based on Medicare Part D data. The estimated annual cost per patient is $6,593.00. Actual out-of-pocket costs depend on your insurance plan and pharmacy.

Aranesp averages $457.00 per Medicare Part D claim — roughly equivalent to a 30-day supply for most patients on standard dosing. Without insurance, expect higher cash-pay prices unless you use a discount program (GoodRx, SingleCare, manufacturer copay assistance). With Medicare or commercial insurance, your out-of-pocket cost depends on your plan's formulary tier and deductible status.

A typical 30-day supply of Aranesp reflects in our Medicare Part D average of $457.00 per claim. Switching to generic Darbepoetin Alfa typically reduces cost by 80-95%. Cash-pay prices vary by pharmacy — comparison shopping (or using GoodRx coupons) often saves 20-50% off the listed price.

Most commercial insurance plans and Medicare Part D plans cover Aranesp, but coverage varies by formulary tier. Insurers typically prefer generic Darbepoetin Alfa (Tier 1, lowest copay) over brand-name Aranesp (Tier 2-3, higher copay). Some plans require prior authorization or step therapy. Check your plan's formulary or call the number on your insurance card to confirm.

Several options for cash-pay patients: (1) Manufacturer patient assistance programs — the manufacturer may offer copay cards or free-drug programs for income-qualified patients; (2) Discount programs like GoodRx, SingleCare, or RxSaver typically save 20-80% off the cash price; (3) Mark Cuban's Cost Plus Drugs offers transparent generic pricing if a generic is available; (4) 340B-eligible community health centers offer drugs at federally negotiated discounts. Switching to generic Darbepoetin Alfa is the single biggest cost reducer if your prescriber is open to it.

Brand-name Aranesp costs more than generic Darbepoetin Alfa primarily for marketing reasons — patients can request the brand from their doctor even when a chemically identical generic exists. The active ingredient and clinical effect are the same.

Yes, a generic version of Aranesp (Darbepoetin Alfa) is available. Generic medications typically cost 80-95% less than brand-name drugs. Ask your pharmacist about generic Darbepoetin Alfa.

Medicare Part D spent $567.0M on Aranesp, covering 86,000 beneficiaries across 1,240,000 claims. This makes it one of the tracked drugs in the Medicare spending dashboard.

Ask your pharmacist about generic Darbepoetin Alfa, which is typically much cheaper. You can also compare prices at different pharmacies, use prescription discount programs (GoodRx, SingleCare, Cost Plus Drugs), or ask your doctor about therapeutic alternatives in the same drug class.

Reading Aranesp's Medicare Pricing

At $457.00 per claim, Aranesp is a mid-priced medication — more than a bargain generic but well short of a specialty product. Drugs in this range are often brands with partial competition, recently-genericized molecules still carrying brand pricing, or moderately complex formulations. The cost is real but rarely catastrophic for kidney disease, and a same-class or generic substitute frequently closes most of the gap.

Aranesp accounts for $567.0M in Medicare Part D spending — a large line item built from 1,240,000 claims across 86,000 beneficiaries. Whether that total is driven more by price or by volume is the useful question: a high $457.00 average claim cost means price is the lever, a modest one means utilization is. Either way, a drug at this spending level is firmly on plan formulary committees' radar.

Because a generic version of Darbepoetin Alfa is on the market, the realistic savings path for Aranesp is straightforward: the generic is therapeutically equivalent and typically costs a fraction of the brand. The friction is usually prescribing habit rather than availability — patients can ask the prescriber to write for the generic, and most plans already steer to it with a lower copay tier. That single switch usually beats coupons, assistance programs, and pharmacy shopping combined.

Every figure here comes from the CMS Medicare Part D Drug Spending dashboard, which reports what the program paid — not the cash price at a retail pharmacy and not a patient's out-of-pocket cost. List prices also overstate the real economics: manufacturers pay confidential rebates to pharmacy benefit managers, so the net price plans actually pay is often well below the sticker. Treat $457.00 as a consistent Medicare-program benchmark for Aranesp, useful for comparing drugs on the same basis, rather than the price any one patient will see at the counter.

Cost data reflects Medicare Part D spending and may not represent retail pharmacy prices. Average cost per claim represents the total drug cost (not patient out-of-pocket) divided by total claims.