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DrugPrice

Noxafil

Posaconazole

Generic availableInfectionsby Merck
$2,721.00
avg cost per claim
+4.2% year-over-year
Reviewed by DrugPrice Editorial Team · Updated
$234.0M
Medicare Spending
86,000
Total Claims
9,600
Beneficiaries
$24,375.00
Annual Cost/Patient

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Why Noxafil Costs $2,721.00 Per Claim

Noxafil (Posaconazole) is used to treat infections. According to CMS Medicare Part D spending data, the program spent $234.0M on this drug, covering 9,600 beneficiaries across 86,000 claims.

A generic version of this drug is available, which means lower-cost alternatives exist. Patients should ask their pharmacist about generic Posaconazole or talk to their doctor about therapeutic alternatives that may cost less.

Price Breakdown

Avg cost per claim (30-day)$2,721.00
Avg annual cost per patient$24,375.00
Total Medicare spending$234.0M
Total claims86,000
Beneficiaries9,600

Drug Details

Brand Name
Noxafil
Generic Name
Posaconazole
Active Ingredient
Posaconazole
Manufacturer
Merck
Dosage Form
N/A
Route
N/A
Condition
Infections
FDA Application
BLA125057

Frequently Asked Questions

Noxafil (Posaconazole) costs an average of $2,721.00 per claim based on Medicare Part D data. The estimated annual cost per patient is $24,375.00. Actual out-of-pocket costs depend on your insurance plan and pharmacy.

Noxafil averages $2,721.00 per Medicare Part D claim — roughly equivalent to a 30-day supply for most patients on standard dosing. Without insurance, expect higher cash-pay prices unless you use a discount program (GoodRx, SingleCare, manufacturer copay assistance). With Medicare or commercial insurance, your out-of-pocket cost depends on your plan's formulary tier and deductible status.

A typical 30-day supply of Noxafil reflects in our Medicare Part D average of $2,721.00 per claim. Switching to generic Posaconazole typically reduces cost by 80-95%. Cash-pay prices vary by pharmacy — comparison shopping (or using GoodRx coupons) often saves 20-50% off the listed price.

Most commercial insurance plans and Medicare Part D plans cover Noxafil, but coverage varies by formulary tier. Insurers typically prefer generic Posaconazole (Tier 1, lowest copay) over brand-name Noxafil (Tier 2-3, higher copay). Some plans require prior authorization or step therapy. Check your plan's formulary or call the number on your insurance card to confirm.

Several options for cash-pay patients: (1) Manufacturer patient assistance programs — the manufacturer may offer copay cards or free-drug programs for income-qualified patients; (2) Discount programs like GoodRx, SingleCare, or RxSaver typically save 20-80% off the cash price; (3) Mark Cuban's Cost Plus Drugs offers transparent generic pricing if a generic is available; (4) 340B-eligible community health centers offer drugs at federally negotiated discounts. Switching to generic Posaconazole is the single biggest cost reducer if your prescriber is open to it.

Brand-name Noxafil costs more than generic Posaconazole primarily for marketing reasons — patients can request the brand from their doctor even when a chemically identical generic exists. The active ingredient and clinical effect are the same.

Yes, a generic version of Noxafil (Posaconazole) is available. Generic medications typically cost 80-95% less than brand-name drugs. Ask your pharmacist about generic Posaconazole.

Medicare Part D spent $234.0M on Noxafil, covering 9,600 beneficiaries across 86,000 claims. This makes it one of the tracked drugs in the Medicare spending dashboard.

Ask your pharmacist about generic Posaconazole, which is typically much cheaper. You can also compare prices at different pharmacies, use prescription discount programs (GoodRx, SingleCare, Cost Plus Drugs), or ask your doctor about therapeutic alternatives in the same drug class.

Reading Noxafil's Medicare Pricing

Noxafil averages $2,721.00 per Part D claim — a high-cost brand medication, well above the commodity-generic range but below the specialty/biologic tier. A price in this band usually signals an on-patent brand with no generic equivalent, or a brand that holds share through prescriber and patient preference even where a generic exists. For infections, the gap between this price and a same-class alternative is where the real savings conversation tends to live.

Medicare spent $234.0M on Noxafil across 86,000 claims and 9,600 beneficiaries — a mid-size line item. Drugs in this tier rarely make headlines but collectively make up the bulk of Part D spending. The interplay between the $2,721.00 average claim cost and the claim volume is what decides whether this drug's total trends up or down year to year.

Because a generic version of Posaconazole is on the market, the realistic savings path for Noxafil is straightforward: the generic is therapeutically equivalent and typically costs a fraction of the brand. The friction is usually prescribing habit rather than availability — patients can ask the prescriber to write for the generic, and most plans already steer to it with a lower copay tier. That single switch usually beats coupons, assistance programs, and pharmacy shopping combined.

Every figure here comes from the CMS Medicare Part D Drug Spending dashboard, which reports what the program paid — not the cash price at a retail pharmacy and not a patient's out-of-pocket cost. List prices also overstate the real economics: manufacturers pay confidential rebates to pharmacy benefit managers, so the net price plans actually pay is often well below the sticker. Treat $2,721.00 as a consistent Medicare-program benchmark for Noxafil, useful for comparing drugs on the same basis, rather than the price any one patient will see at the counter.

Cost data reflects Medicare Part D spending and may not represent retail pharmacy prices. Average cost per claim represents the total drug cost (not patient out-of-pocket) divided by total claims.