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How Much Does Morphine Cost With Medicare?

Morphine (Morphine Sulfate) costs an average of $25 per Medicare Part D claim, with total Medicare spending of $123.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.

Key Facts: Morphine Cost

Medicare Part D avg
$25/claim
Likely Part D tier
Tier 1 (generic)
Annual cost/patient
$212
Generic available
Yes — Morphine Sulfate
Manufacturer
Various
Treats
Pain
YoY price change
-22.4%

Source: CMS Medicare Part D Spending Dashboard. Tier placement inferred from typical formulary norms — confirm with your specific Part D plan.

Morphine Medicare Coverage & Out-of-Pocket Cost

Morphine is covered under Medicare Part D, with the program paying an average of $25 per prescription fill. Morphine typically falls on Tier 1 (generic) of standard Part D formularies. Typical copay: $0-$10 per fill on most Medicare Part D plans.

Your actual out-of-pocket cost depends on three factors: (1) formulary tier — your plan's specific placement; (2) deductible status — most plans require you to meet up to a $590 deductible (2025) before copays kick in; (3) coverage phase — initial coverage, then the donut hole was eliminated in 2025, replaced by a hard $2,000 annual out-of-pocket cap under the Inflation Reduction Act. Once you hit $2,000 in true out-of-pocket spending, the rest of your Part D drugs are free for the year.

Because generic Morphine Sulfate is available, the single biggest savings move is asking your pharmacist about generic substitution. Generics typically sit on Tier 1 with copays under $10, vs Tier 2-3 placement for brand-name Morphine. Most states allow automatic substitution unless your prescriber writes "dispense as written."

For cash-pay or commercial insurance scenarios, compare prices using GoodRx, SingleCare, or Cost Plus Drugs before filling — discount-program prices sometimes beat Part D copays for lower-cost generics.

Morphine is manufactured by Various and prescribed primarily for Pain. In the most recent Medicare Part D data, 4,860,000 claims were filed for 580,000 unique beneficiaries, at an average cost of $25 per claim. Average annual cost per beneficiary is $212.

Year over year, Medicare spending on Morphine has decreased by -22.4%. Because a generic version of Morphine Sulfate is available, patients can often substitute to reduce out-of-pocket costs. Its patent expires 2023-01-31.

Key Data

MetricValue
Avg Cost Per Claim$25
Total Medicare Spending$123.0M
Total Claims4,860,000
Beneficiaries580,000
Generic AvailableYes
Year-Over-Year Change-22.4%

Frequently Asked Questions

Medicare Part D pays an average of $25 per claim for Morphine. Morphine is typically placed on Tier 1 (generic) of standard Part D formularies. Typical copay: $0-$10 per fill on most Medicare Part D plans. As of 2025, total annual out-of-pocket on Part D is capped at $2,000 under the Inflation Reduction Act.

Yes. Morphine appears in Medicare Part D claims data, with 580,000 beneficiaries filling 4,860,000 prescriptions in the latest year. Specific coverage depends on your plan's formulary — call the number on your insurance card or check the plan's Summary of Benefits to confirm prior authorization, step therapy, or quantity limit requirements.

Morphine (Morphine Sulfate) costs an average of $25 per Medicare Part D claim, with total Medicare spending of $123.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.

Yes. A generic version of Morphine Sulfate is available, which typically costs 80-95% less than brand-name Morphine. Ask your pharmacist about generic substitution — most state laws allow automatic substitution unless your prescriber writes "dispense as written."

Medicare beneficiaries cannot use manufacturer copay cards (anti-kickback statute), but several options exist: (1) Apply to charity copay foundations like the PAN Foundation, NeedyMeds, HealthWell Foundation, or Patient Advocate Foundation — many cover pain drugs; (2) Ask your prescriber about therapeutic alternatives in the same drug class that may be on a lower tier; (3) For some drugs, paying cash via GoodRx or Cost Plus Drugs can beat your Medicare copay — always compare before filling; (4) If your income is below 150% of the federal poverty level, you may qualify for the Medicare Extra Help (Low-Income Subsidy) program, which reduces Part D costs to near-zero.

Morphine is manufactured by Various. The FDA application number is BLA125057.

Morphine (Morphine Sulfate) is primarily prescribed for Pain.

Medicare Part D spending on Morphine has decreased -22.4% year over year. Total program spending reached $123.0M in the latest reporting year.

Morphine (Morphine Sulfate) costs an average of $25 per Medicare Part D claim, with total Medicare spending of $123.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.

The data source behind this answer is CMS Medicare Part D Drug Spending data. Every figure on the page traces back to that source; the methodology page describes the inputs and the refresh cadence in full detail.

For readers turning this answer into action: cross-reference against the underlying CMS Medicare Part D Drug Spending data record before acting on time-sensitive decisions. The site renders the data as it was published; subsequent revisions can shift the picture, and the live federal data is always the authoritative current reference.

Source: CMS Medicare Part D Spending, 2026.