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How Much Does Semglee Cost With Medicare?

Semglee (Insulin Glargine-yfgn) costs an average of $139 per Medicare Part D claim, with total Medicare spending of $345.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.

Key Facts: Semglee Cost

Medicare Part D avg
$139/claim
Likely Part D tier
Tier 2 (preferred brand)
Annual cost/patient
$1,206
Generic available
Yes — Insulin Glargine-yfgn
Manufacturer
Viatris
Treats
Diabetes
YoY price change
+42.3%

Source: CMS Medicare Part D Spending Dashboard. Tier placement inferred from typical formulary norms — confirm with your specific Part D plan.

Semglee Medicare Coverage & Out-of-Pocket Cost

Semglee is covered under Medicare Part D, with the program paying an average of $139 per prescription fill. Semglee typically falls on Tier 2 (preferred brand) of standard Part D formularies. Typical copay: $25-$50 per fill on most Medicare Part D plans.

Your actual out-of-pocket cost depends on three factors: (1) formulary tier — your plan's specific placement; (2) deductible status — most plans require you to meet up to a $590 deductible (2025) before copays kick in; (3) coverage phase — initial coverage, then the donut hole was eliminated in 2025, replaced by a hard $2,000 annual out-of-pocket cap under the Inflation Reduction Act. Once you hit $2,000 in true out-of-pocket spending, the rest of your Part D drugs are free for the year.

Because generic Insulin Glargine-yfgn is available, the single biggest savings move is asking your pharmacist about generic substitution. Generics typically sit on Tier 1 with copays under $10, vs Tier 2-3 placement for brand-name Semglee. Most states allow automatic substitution unless your prescriber writes "dispense as written."

For cash-pay or commercial insurance scenarios, compare prices using GoodRx, SingleCare, or Cost Plus Drugs before filling — discount-program prices sometimes beat Part D copays for lower-cost generics.

Semglee is manufactured by Viatris and prescribed primarily for Diabetes. In the most recent Medicare Part D data, 2,480,000 claims were filed for 286,000 unique beneficiaries, at an average cost of $139 per claim. Average annual cost per beneficiary is $1,206.

Year over year, Medicare spending on Semglee has increased by +42.3%. Because a generic version of Insulin Glargine-yfgn is available, patients can often substitute to reduce out-of-pocket costs. Its patent expires 2023-01-31.

Key Data

MetricValue
Avg Cost Per Claim$139
Total Medicare Spending$345.0M
Total Claims2,480,000
Beneficiaries286,000
Generic AvailableYes
Year-Over-Year Change+42.3%

Frequently Asked Questions

Medicare Part D pays an average of $139 per claim for Semglee. Semglee is typically placed on Tier 2 (preferred brand) of standard Part D formularies. Typical copay: $25-$50 per fill on most Medicare Part D plans. As of 2025, total annual out-of-pocket on Part D is capped at $2,000 under the Inflation Reduction Act.

Yes. Semglee appears in Medicare Part D claims data, with 286,000 beneficiaries filling 2,480,000 prescriptions in the latest year. Specific coverage depends on your plan's formulary — call the number on your insurance card or check the plan's Summary of Benefits to confirm prior authorization, step therapy, or quantity limit requirements.

Semglee (Insulin Glargine-yfgn) costs an average of $139 per Medicare Part D claim, with total Medicare spending of $345.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.

Yes. A generic version of Insulin Glargine-yfgn is available, which typically costs 80-95% less than brand-name Semglee. Ask your pharmacist about generic substitution — most state laws allow automatic substitution unless your prescriber writes "dispense as written."

Medicare beneficiaries cannot use manufacturer copay cards (anti-kickback statute), but several options exist: (1) Apply to charity copay foundations like the PAN Foundation, NeedyMeds, HealthWell Foundation, or Patient Advocate Foundation — many cover diabetes drugs; (2) Ask your prescriber about therapeutic alternatives in the same drug class that may be on a lower tier; (3) For some drugs, paying cash via GoodRx or Cost Plus Drugs can beat your Medicare copay — always compare before filling; (4) If your income is below 150% of the federal poverty level, you may qualify for the Medicare Extra Help (Low-Income Subsidy) program, which reduces Part D costs to near-zero.

Semglee is manufactured by Viatris. The FDA application number is BLA125057.

Semglee (Insulin Glargine-yfgn) is primarily prescribed for Diabetes.

Medicare Part D spending on Semglee has increased +42.3% year over year. Total program spending reached $345.0M in the latest reporting year.

Semglee (Insulin Glargine-yfgn) costs an average of $139 per Medicare Part D claim, with total Medicare spending of $345.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.

The data source behind this answer is CMS Medicare Part D Drug Spending data. Every figure on the page traces back to that source; the methodology page describes the inputs and the refresh cadence in full detail.

A practical caveat: the headline answer above reflects the most recent CMS Medicare Part D Drug Spending data vintage; underlying data is often revised for months after first publication, and the right reference for any specific decision is whichever vintage is current at the time of the decision. The as-of date is stamped on every page.

Source: CMS Medicare Part D Spending, 2026.