How Much Does Trodelvy Cost With Medicare?
Trodelvy (Sacituzumab Govitecan) costs an average of $15,643 per Medicare Part D claim, with total Medicare spending of $876.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.
Key Facts: Trodelvy Cost
- Medicare Part D avg
- $15,643/claim
- Likely Part D tier
- Tier 4-5 (specialty)
- Annual cost/patient
- $136,875
- Generic available
- Yes — Sacituzumab Govitecan
- Manufacturer
- Gilead
- Treats
- Cancer
- YoY price change
- +68.4%
Source: CMS Medicare Part D Spending Dashboard. Tier placement inferred from typical formulary norms — confirm with your specific Part D plan.
Trodelvy Medicare Coverage & Out-of-Pocket Cost
Trodelvy is covered under Medicare Part D, with the program paying an average of $15,643 per prescription fill. Trodelvy typically falls on Tier 4-5 (specialty) of standard Part D formularies. Specialty drugs use coinsurance (25-33% of plan-negotiated price), not flat copays. The 2025 Part D annual out-of-pocket cap is $2,000.
Your actual out-of-pocket cost depends on three factors: (1) formulary tier — your plan's specific placement; (2) deductible status — most plans require you to meet up to a $590 deductible (2025) before copays kick in; (3) coverage phase — initial coverage, then the donut hole was eliminated in 2025, replaced by a hard $2,000 annual out-of-pocket cap under the Inflation Reduction Act. Once you hit $2,000 in true out-of-pocket spending, the rest of your Part D drugs are free for the year.
Because generic Sacituzumab Govitecan is available, the single biggest savings move is asking your pharmacist about generic substitution. Generics typically sit on Tier 1 with copays under $10, vs Tier 2-3 placement for brand-name Trodelvy. Most states allow automatic substitution unless your prescriber writes "dispense as written."
For cash-pay or commercial insurance scenarios, compare prices using GoodRx, SingleCare, or Cost Plus Drugs before filling — discount-program prices sometimes beat Part D copays for lower-cost generics.
Trodelvy is manufactured by Gilead and prescribed primarily for Cancer. In the most recent Medicare Part D data, 56,000 claims were filed for 6,400 unique beneficiaries, at an average cost of $15,643 per claim. Average annual cost per beneficiary is $136,875.
Year over year, Medicare spending on Trodelvy has increased by +68.4%. Because a generic version of Sacituzumab Govitecan is available, patients can often substitute to reduce out-of-pocket costs. Its patent expires 2023-01-31.
Key Data
| Metric | Value |
|---|---|
| Avg Cost Per Claim | $15,643 |
| Total Medicare Spending | $876.0M |
| Total Claims | 56,000 |
| Beneficiaries | 6,400 |
| Generic Available | Yes |
| Year-Over-Year Change | +68.4% |
Other Drugs for Cancer
Frequently Asked Questions
Medicare Part D pays an average of $15,643 per claim for Trodelvy. Trodelvy is typically placed on Tier 4-5 (specialty) of standard Part D formularies. Specialty drugs use coinsurance (25-33% of plan-negotiated price), not flat copays. The 2025 Part D annual out-of-pocket cap is $2,000. As of 2025, total annual out-of-pocket on Part D is capped at $2,000 under the Inflation Reduction Act.
Yes. Trodelvy appears in Medicare Part D claims data, with 6,400 beneficiaries filling 56,000 prescriptions in the latest year. Specific coverage depends on your plan's formulary — call the number on your insurance card or check the plan's Summary of Benefits to confirm prior authorization, step therapy, or quantity limit requirements.
Trodelvy (Sacituzumab Govitecan) costs an average of $15,643 per Medicare Part D claim, with total Medicare spending of $876.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.
Yes. A generic version of Sacituzumab Govitecan is available, which typically costs 80-95% less than brand-name Trodelvy. Ask your pharmacist about generic substitution — most state laws allow automatic substitution unless your prescriber writes "dispense as written."
Medicare beneficiaries cannot use manufacturer copay cards (anti-kickback statute), but several options exist: (1) Apply to charity copay foundations like the PAN Foundation, NeedyMeds, HealthWell Foundation, or Patient Advocate Foundation — many cover cancer drugs; (2) Ask your prescriber about therapeutic alternatives in the same drug class that may be on a lower tier; (3) For some drugs, paying cash via GoodRx or Cost Plus Drugs can beat your Medicare copay — always compare before filling; (4) If your income is below 150% of the federal poverty level, you may qualify for the Medicare Extra Help (Low-Income Subsidy) program, which reduces Part D costs to near-zero.
Trodelvy is manufactured by Gilead. The FDA application number is BLA125057.
Trodelvy (Sacituzumab Govitecan) is primarily prescribed for Cancer.
Medicare Part D spending on Trodelvy has increased +68.4% year over year. Total program spending reached $876.0M in the latest reporting year.
Trodelvy (Sacituzumab Govitecan) costs an average of $15,643 per Medicare Part D claim, with total Medicare spending of $876.0M in the latest year. A generic version is available, which may reduce out-of-pocket costs.
The data source behind this answer is CMS Medicare Part D Drug Spending data. Every figure on the page traces back to that source; the methodology page describes the inputs and the refresh cadence in full detail.
For readers turning this answer into action: cross-reference against the underlying CMS Medicare Part D Drug Spending data record before acting on time-sensitive decisions. The site renders the data as it was published; subsequent revisions can shift the picture, and the live federal data is always the authoritative current reference.
Source: CMS Medicare Part D Spending, 2026.