How Much Does Trulicity Cost With Medicare?
Trulicity (Dulaglutide) costs an average of $473 per Medicare Part D claim, with total Medicare spending of $4215.0M in the latest year. No generic alternative is currently available.
Key Facts: Trulicity Cost
- Medicare Part D avg
- $473/claim
- Likely Part D tier
- Tier 3 (non-preferred brand)
- Annual cost/patient
- $4,279
- Generic available
- No
- Manufacturer
- Eli Lilly
- Treats
- Diabetes
- Patent expires
- 2027-09-18
- YoY price change
- -4.8%
Source: CMS Medicare Part D Spending Dashboard. Tier placement inferred from typical formulary norms — confirm with your specific Part D plan.
Trulicity Medicare Coverage & Out-of-Pocket Cost
Trulicity is covered under Medicare Part D, with the program paying an average of $473 per prescription fill. Trulicity typically falls on Tier 3 (non-preferred brand) of standard Part D formularies. Typical copay: $40-$100 per fill, depending on plan formulary.
Your actual out-of-pocket cost depends on three factors: (1) formulary tier — your plan's specific placement; (2) deductible status — most plans require you to meet up to a $590 deductible (2025) before copays kick in; (3) coverage phase — initial coverage, then the donut hole was eliminated in 2025, replaced by a hard $2,000 annual out-of-pocket cap under the Inflation Reduction Act. Once you hit $2,000 in true out-of-pocket spending, the rest of your Part D drugs are free for the year.
No generic is currently available for Trulicity. Medicare beneficiaries cannot use manufacturer copay cards (anti-kickback statute prohibits them for federal program enrollees), but charity foundations such as the PAN Foundation, NeedyMeds, and the HealthWell Foundation offer copay grants for many diabetes drugs. The Medicare Extra Help (LIS) program also reduces Part D costs to near-zero for income-qualified beneficiaries (under 150% of the federal poverty level).
For cash-pay or commercial insurance scenarios, compare prices using GoodRx, SingleCare, or Cost Plus Drugs before filling — discount-program prices sometimes beat Part D copays for lower-cost generics.
Trulicity is manufactured by Eli Lilly and prescribed primarily for Diabetes. In the most recent Medicare Part D data, 8,920,000 claims were filed for 985,000 unique beneficiaries, at an average cost of $473 per claim. Average annual cost per beneficiary is $4,279.
Year over year, Medicare spending on Trulicity has decreased by -4.8%. No generic substitute is available, so the brand-name price reflects the full market cost. Its patent expires 2027-09-18.
Trulicity belongs to the Diabetes Medications class. Metformin reduces liver glucose production ($4/month generic). GLP-1 agonists (Ozempic, Trulicity) mimic gut hormones to stimulate insulin release and reduce appetite. SGLT2 inhibitors (Jardiance, Farxiga) block glucose reabsorption in kidneys. DPP-4 inhibitors (Januvia) enhance the body's own incretin hormones. Insulin directly replaces what the body can't produce.
Key Data
| Metric | Value |
|---|---|
| Avg Cost Per Claim | $473 |
| Total Medicare Spending | $4215.0M |
| Total Claims | 8,920,000 |
| Beneficiaries | 985,000 |
| Generic Available | No |
| Year-Over-Year Change | -4.8% |
Other Drugs for Diabetes
Frequently Asked Questions
Medicare Part D pays an average of $473 per claim for Trulicity. Trulicity is typically placed on Tier 3 (non-preferred brand) of standard Part D formularies. Typical copay: $40-$100 per fill, depending on plan formulary. As of 2025, total annual out-of-pocket on Part D is capped at $2,000 under the Inflation Reduction Act.
Yes. Trulicity appears in Medicare Part D claims data, with 985,000 beneficiaries filling 8,920,000 prescriptions in the latest year. Specific coverage depends on your plan's formulary — call the number on your insurance card or check the plan's Summary of Benefits to confirm prior authorization, step therapy, or quantity limit requirements.
Trulicity (Dulaglutide) costs an average of $473 per Medicare Part D claim, with total Medicare spending of $4215.0M in the latest year. No generic alternative is currently available.
No. As of the latest FDA Orange Book data, there is no generic version of Trulicity (Dulaglutide). Patent protection extends until 2027-09-18, after which generics may enter the market.
Medicare beneficiaries cannot use manufacturer copay cards (anti-kickback statute), but several options exist: (1) Apply to charity copay foundations like the PAN Foundation, NeedyMeds, HealthWell Foundation, or Patient Advocate Foundation — many cover diabetes drugs; (2) Ask your prescriber about therapeutic alternatives in the same drug class that may be on a lower tier; (3) For some drugs, paying cash via GoodRx or Cost Plus Drugs can beat your Medicare copay — always compare before filling; (4) If your income is below 150% of the federal poverty level, you may qualify for the Medicare Extra Help (Low-Income Subsidy) program, which reduces Part D costs to near-zero.
Trulicity is manufactured by Eli Lilly. The FDA application number is BLA125469.
Trulicity (Dulaglutide) is primarily prescribed for Diabetes.
Medicare Part D spending on Trulicity has decreased -4.8% year over year. Total program spending reached $4215.0M in the latest reporting year.
Trulicity (Dulaglutide) costs an average of $473 per Medicare Part D claim, with total Medicare spending of $4215.0M in the latest year. No generic alternative is currently available.
The data source behind this answer is CMS Medicare Part D Drug Spending data. Every figure on the page traces back to that source; the methodology page describes the inputs and the refresh cadence in full detail.
For readers turning this answer into action: cross-reference against the underlying CMS Medicare Part D Drug Spending data record before acting on time-sensitive decisions. The site renders the data as it was published; subsequent revisions can shift the picture, and the live federal data is always the authoritative current reference.
Source: CMS Medicare Part D Spending, 2026.