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DrugPrice

Entresto vs Skyrizi

Side-by-side drug price comparison from Medicare Part D data

Verdict

Entresto costs 92% less per claim than Skyrizi ($379.00 vs $4475.00). Neither drug has a generic alternative available. Total Medicare spending: Entresto at $4.8B vs Skyrizi at $2.3B.

MetricEntrestoSkyrizi
Avg Cost per Claim
Average cost Medicare pays per prescription claim
$379*$4,475
Total Medicare Spending
Total Medicare Part D spending on this drug
$4.8B$2.3B
Total Claims12,560,000524,000
Year-over-Year Change
Price change from prior year (lower is better for patients)
18.3%*42.8%
Generic AvailableNoNo
ConditionHeart FailureAutoimmune Diseases
Total Beneficiaries1,085,00078,000

Entresto costs 92% less per claim than Skyrizi ($379.00 vs $4475.00). Neither drug has a generic alternative available. Total Medicare spending: Entresto at $4.8B vs Skyrizi at $2.3B.

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