Revlimid vs Entresto
Side-by-side drug price comparison from Medicare Part D data
Verdict
Entresto costs 97% less per claim than Revlimid ($379.00 vs $12786.00). Neither drug has a generic alternative available. Total Medicare spending: Revlimid at $7.8B vs Entresto at $4.8B.
| Metric | Revlimid | Entresto |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $12,786 | $379* |
| Total Medicare Spending Total Medicare Part D spending on this drug | $7.8B | $4.8B |
| Total Claims | 612,000 | 12,560,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | -3.4%* | 18.3% |
| Generic Available | No | No |
| Condition | Cancer | Heart Failure |
| Total Beneficiaries | 58,000 | 1,085,000 |
Entresto costs 97% less per claim than Revlimid ($379.00 vs $12786.00). Neither drug has a generic alternative available. Total Medicare spending: Revlimid at $7.8B vs Entresto at $4.8B.
Explore More
The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both Revlimid and Entresto. What follows is the interpretation — which specific axes carry the most weight for Revlimid versus Entresto, and which differences are large enough to influence a real decision.
For households or analysts using this comparison as a decision input, the right framing is usually not "which is better" in aggregate but "which is better for the specific decision in front of you." CMS Medicare Part D Drug Spending data captures the raw data; the framing depends on whether the question is investment, residency, planning, or research.
Source: CMS Medicare Part D Spending, 2026.