Trulicity vs Repatha
Side-by-side drug price comparison from Medicare Part D data
Verdict
Trulicity costs 38% less per claim than Repatha ($473.00 vs $757.00). Neither drug has a generic alternative available. Total Medicare spending: Trulicity at $4.2B vs Repatha at $2.6B.
| Metric | Trulicity | Repatha |
|---|---|---|
| Avg Cost per Claim Average cost Medicare pays per prescription claim | $473* | $757 |
| Total Medicare Spending Total Medicare Part D spending on this drug | $4.2B | $2.6B |
| Total Claims | 8,920,000 | 3,420,000 |
| Year-over-Year Change Price change from prior year (lower is better for patients) | -4.8%* | 24.6% |
| Generic Available | No | No |
| Condition | Diabetes | High Cholesterol |
| Total Beneficiaries | 985,000 | 398,000 |
Trulicity costs 38% less per claim than Repatha ($473.00 vs $757.00). Neither drug has a generic alternative available. Total Medicare spending: Trulicity at $4.2B vs Repatha at $2.6B.
Explore More
The side-by-side above pulls the CMS Medicare Part D Drug Spending data data for both entity A and entity B. What follows is the interpretation — which specific axes carry the most weight for entity A versus entity B, and which differences are large enough to influence a real decision.
Practical use of the comparison: read the data above, then drill into the individual entity A and entity B detail pages for the underlying breakdown. A pairwise comparison answers the relative question; the per-entity pages answer the absolute question.
Source: CMS Medicare Part D Spending, 2026.