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DrugPrice

Lybalvi

Olanzapine/Samidorphan

Generic availableMental Healthby Alkermes
$375.00
avg cost per claim
+68.4% year-over-year
$234.0M
Medicare Spending
624,000
Total Claims
72,000
Beneficiaries
$3,250.00
Annual Cost/Patient

Why Lybalvi Costs $375.00 Per Claim

Lybalvi (Olanzapine/Samidorphan) is used to treat mental health. According to CMS Medicare Part D spending data, the program spent $234.0M on this drug, covering 72,000 beneficiaries across 624,000 claims.

A generic version of this drug is available, which means lower-cost alternatives exist. Patients should ask their pharmacist about generic Olanzapine/Samidorphan or talk to their doctor about therapeutic alternatives that may cost less.

Spending on Lybalvi increased by +68.4% year-over-year, driven by rapidly growing utilization and potential price increases.

Price Breakdown

Avg cost per claim (30-day)$375.00
Avg annual cost per patient$3,250.00
Total Medicare spending$234.0M
Total claims624,000
Beneficiaries72,000

Drug Details

Brand Name
Lybalvi
Generic Name
Olanzapine/Samidorphan
Active Ingredient
Olanzapine/Samidorphan
Manufacturer
Alkermes
Dosage Form
N/A
Route
N/A
Condition
Mental Health
FDA Application
BLA125057

Frequently Asked Questions

Lybalvi (Olanzapine/Samidorphan) costs an average of $375.00 per claim based on Medicare Part D data. The estimated annual cost per patient is $3,250.00. Actual out-of-pocket costs depend on your insurance plan and pharmacy.

Yes, a generic version of Lybalvi (Olanzapine/Samidorphan) is available. Generic medications typically cost 80-95% less than brand-name drugs. Ask your pharmacist about generic Olanzapine/Samidorphan.

Medicare Part D spent $234.0M on Lybalvi, covering 72,000 beneficiaries across 624,000 claims. This makes it one of the tracked drugs in the Medicare spending dashboard.

Ask your pharmacist about generic Olanzapine/Samidorphan, which is typically much cheaper. You can also compare prices at different pharmacies, use prescription discount programs, or ask your doctor about therapeutic alternatives in the same drug class.

Cost data reflects Medicare Part D spending and may not represent retail pharmacy prices. Average cost per claim represents the total drug cost (not patient out-of-pocket) divided by total claims.